Tuesday, January 12, 2021

Early Detection of Cognitive Decline in Type 1 Diabetics

Article: Routine eye scans may give clues to cognitive decline in diabetes
Source: Joslin Diabetes Center at Harvard Medical School, via ScienceDaily
Published: January 4, 2021

Ocular Coherence Tomography (OCT) and its most recent additional function of angiography (OCTA) have been explored in recent years as a means of early detection of neurodegenerative diseases such as Alzheimer's. The retina, being an extension of the brain (specifically the diencephalon), allows for a unique, noninvasive, and comparatively inexpensive view into conditions that affect the central nervous system. What was new to me, i.e., what this article introduced me to, is the potential connection between diabetes and Alzheimer's disease. The researchers found associations between proliferative diabetic retinopathy (PDR) and certain memory and psychomotor tasks. The small and somewhat cloistered study, comprising 129 participants, investigated the link for people with Type 1 diabetes, but the researchers plan on future studies for the larger population of people who are affected by Type 2 diabetes.

My rating of this study:

Fickweiler W, Wolfson EA, Paniagua SM, et al. "Association of Cognitive Function and Retinal Neural and Vascular Structure in Type 1 Diabetes." The Journal of Clinical Endocrinology & Metabolism.  Published online 30 December 2020. https://doi.org/10.1210/clinem/dgaa921

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