NEI's AGI Functional Imaging Consortium Highlights

Article: Audacious projects develop imaging technology to aid eye tissue regeneration
Source: National Eye Institute
Published: April 21, 2021

The article summarized here is itself a kind of "Week in Review" highlighting updates to five projects from the National Eye Institute's AGI functional imaging consortium. The highlights include projects in (1) noninvasive methods to record nerve cell firing, (2) retinal camera technologies that compensate for eye movements, (3) two-photon excitation microscopy combined with adaptive optics to noninvasively and dynamically observe the integration of transplanted retinal cells, (4) two-photon excitation microscopy to noninvasively visualize vitamin A metabolic defects in the retina, and (5) diffusion basis spectrum imaging to noninvasively detect and quantify axonal injury and optic nerve damage. These five projects represent examples of advances in functional noninvasive imaging technologies to aid in the diagnosis and treatment of degenerative eye diseases and provide a foundation for enrolling patients in clinical trials for regenerative therapies.